inhibit the action or formation of clotting factors = prevent clot formation *Do NOT dissolve already formed thrombus*-Antithrombotic drugs-only given prophylactically since there is NO DIRECT effect on a blood clot that has already been formed. Maintenance dose: 2 to 10 mg orally once a day Comments : -Initial dose is influenced by age, race, body weight, gender, concomitant medications, comorbidities, genetic variation, and possibly other factors. How to use Coumadin. Read the Medication Guide provided by your pharmacist before you start taking warfarin and each time you get a refill. If you have any questions, ask your doctor or pharmacist. -Only given orally-Often started after Heparin is discontinued-Used prophylactically (to prevent) for patients with a-fib-Dosage adjusted to INR (international normalized ratio) and PT (prothrombin) Consumer information about the medication WARFARIN - ORAL (Coumadin), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug WARFARIN - ORAL. DESCRIPTION. COUMADIN (warfarin sodium) tablets and COUMADIN (warfarin sodium) for injection contain warfarin sodium, an anticoagulant that acts by inhibiting vitamin K⌈dependent coagulation factors. Heparin must be given by injection, whereas warfarin is available orally. Warfarin has a long half-life and need only be given once a day. Heparin can also cause a prothrombotic condition, Warfarin has a long half-life and need only be given once a day. orally at a dose of 2.5 to 5 mg (INR reduction expected to occur within 24 hours) or intravenously at a dose of 1-2.5 mg by slow (over 1 hour) IV infusion (INR reduction expected to occur in 8-12 hours). COUMADIN ® is indicated for: • Prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism (PE). • Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation (AF) and/or cardiac valve replacement. Answer: A B) Warfarin (Coumadin, Jantoven) is given orally. C) Aspirin is given orally. D) This is given orally.